She has been an active contributor to clinical trials for over three decades. She has been part of senior advisory panels for the NIH. These include the Clinical Applications and Prevention Advisory Committee for the National Heart, Lung, and Blood Institute and, notably, the National Advisory Eye Council.
She helped to pioneer a clinical trial model for industry sponsored trials where the interim and often final analyses are performed by an academic group external to the industry sponsor and to the data management center. Initially, many clinical trialists thought this model was not feasible or necessary but with time it has become a standard. The list of trials for which she has served as the “independent” statistician supporting the DMC is long and includes many important trials in cardiology, neurology, diabetes and emergency care to mention a few. She has served the Society in every way possible.